Method Development and Validation

EPL BAS provides method development and validation services for the agricultural biotechnology and chemical industries as well as the feed and food ingredient industries. Our scientists have broad experience in the analysis of:

• agrochemical residues
• active ingredients (AI)
• impurities
• plants
• seeds
• feed
• processed fractions
• product contaminants
• product adulteration
• bio-pesticides
• bio-rational products
• functional foods

Our scientists use the following instrumentation:

• High Performance/Pressure Liquid Chromatography (HPLC) and Ultra High Performance/Pressure Liquid Chromatography (UHPLC)
• HPLC and UHPLC detection methods including tandem mass spectrometry (MS/MS), refractive index, evaporative light scattering (ELS), fluorescence and ultraviolet detection
• Gas Chromatography (GC)
• GC detection methods include MS, MS/MS and flame-ionization (GC/FID)
• Variety of specialized instrumentation for nutritional analysis

Other techniques include:

• Polymerase Chain Reaction (PCR)
• Enzyme-Linked Immunosorbent Assay (ELISA)
• Southern Blot
• Western Blot
• SDS Page
• Cryomill, GenoGrinder, and other high-throughput methods for both chemistry and molecular biology

Your need for development and/or validation of a new method may originate with research requirements, new product support, regulatory requirements or other specialized projects. EPL BAS can customize our support in these areas to your exact specifications.

All our work is conducted in compliance with our Quality Management System, including non-regulatory method development and method validation, so you can always have confidence in the information generated from this system.

For feed and food ingredient support, documentation and criteria used for validation are in conformance with ISO 17025:2005.

For regulatory Good Laboratory Practice (GLP) compliant method validation work including Independent Laboratory Validations (ILVs), work can be carried out to meet the applicable requirements including:

• SANCO/3029/99 Rev. 4
• SANCO/825/00 Rev. 8.1
• OCSPP/OPTTS 860.1340
• OCSPP/OPPTS 850.6100
• PMRA Dir98-02
• ENV/JM/MONO/2007/17 OECD
• PR Notice 86-5/ PR Notice 96-1
• US EPA 40CFR Part 160
• OCSPP/OPPTS 830.1800

For more information or to request a quote please click here